Wake Blog

    Insights & Research

    Thoughts on psychedelic medicine, neuroscience, wellness, and the future of mental health care.

    Clinical Research of Psychedelics using Wearables
    psychedelics
    wearables
    biosensors

    Clinical Research of Psychedelics using Wearables

    Continuous wearable biosensors — HRV, EDA, EEG, and actigraphy — are poised to close the measurement gap in psychedelic-assisted therapy research, enabling real-time physiological monitoring across the full arc of a dosing session and integration period.

    WakeMarch 14, 2026
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    Family Constellation Therapy for Psychedelics
    family constellation therapy
    psychedelics
    intergenerational trauma

    Family Constellation Therapy for Psychedelics

    An evidence-informed exploration of how Family Constellation Therapy intersects with psychedelic-assisted therapy — the science of epigenetic trauma transmission, the critical ethics of the Hellinger legacy, and a responsible clinical framework for working with ancestral material in expanded states.

    WakeMarch 11, 2026
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    Stacking Functional Mushrooms: Is Combining Lion's Mane, Reishi, Cordyceps, and Turkey Tail Worth It?
    Mushroom Stacking
    Functional Mushrooms
    Synergy

    Stacking Functional Mushrooms: Is Combining Lion's Mane, Reishi, Cordyceps, and Turkey Tail Worth It?

    Functional mushrooms are increasingly taken in combination — but is there actual evidence for synergy, or is it marketing? We review the science on mushroom blends, explain the complementary mechanisms, and offer practical stacking guidance.

    WakeMarch 8, 2026
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    ACT for Psychedelics
    ACT
    psychedelics
    psilocybin

    ACT for Psychedelics

    How Acceptance and Commitment Therapy bridges the gap between psychedelic insight and lasting behavioral change — the science of psychological flexibility, the REBUS model, and a practical ACT-informed framework for preparation and integration.

    WakeMarch 3, 2026
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    Turkey Tail Mushroom: The Immune Champion With FDA-Recognized Research
    Turkey Tail
    Immune Support
    Gut Health

    Turkey Tail Mushroom: The Immune Champion With FDA-Recognized Research

    Turkey Tail (Trametes versicolor) is the only functional mushroom with an FDA-approved clinical trial for cancer patients. We break down the PSK and PSP research, gut microbiome findings, and what distinguishes it from the supplement noise.

    WakeFebruary 19, 2026
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    Cordyceps: The Performance Mushroom — Clinical Evidence on Energy, Endurance, and Vitality
    Cordyceps
    Athletic Performance
    Energy

    Cordyceps: The Performance Mushroom — Clinical Evidence on Energy, Endurance, and Vitality

    Once worth more than gold in Tibet, Cordyceps has found a new audience in athletes and biohackers. Clinical trials show measurable gains in VO2 max and endurance — here's what the science says about how it works and how much to take.

    WakeFebruary 12, 2026
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    IFS for Psychedelics
    IFS
    psychedelics
    psilocybin

    IFS for Psychedelics

    A comprehensive exploration of how Internal Family Systems therapy and psychedelic-assisted therapy converge — what the evidence shows, how an IFS-informed session works in practice, and why these two modalities speak the same language.

    WakeFebruary 5, 2026
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    Reishi Mushroom: The Immune Modulator With 2,000 Years of Use — What Clinical Trials Show
    Reishi
    Immune Support
    Adaptogen

    Reishi Mushroom: The Immune Modulator With 2,000 Years of Use — What Clinical Trials Show

    Reishi (Ganoderma lucidum) is perhaps the most revered medicinal mushroom in Eastern medicine. Modern clinical trials reveal real benefits for immunity, fatigue, and sleep — but also important nuances the label won't tell you.

    WakeJanuary 22, 2026
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    Lion's Mane Mushroom: Clinical Evidence for Brain Health and Beyond
    Lion's Mane
    Nootropics
    Brain Health

    Lion's Mane Mushroom: Clinical Evidence for Brain Health and Beyond

    Lion's Mane (Hericium erinaceus) is the only mushroom known to stimulate nerve growth factor synthesis. We review the clinical evidence on cognitive function, anxiety, gut health, and what the research actually says about dosing.

    WakeJanuary 8, 2026
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